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Index > Protein center > HMMR(Gene name) > Human
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  • HMMR (Gene name),
  • Hyaluronan mediated motility receptor (Protein name ),  HMMR_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    HMMR(IHABP;RHAMM);
    Protein name:
    Hyaluronan mediated motility receptor;
    Alternative:
    Receptor for hyaluronan-mediated motility;Intracellular hyaluronic acid-binding protein;
    CD:
    CD168;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Subunit of the HARC complex.
    Function:
    Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the focal adhesion kinase occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.
    Subcellular Location:
    Cell surface Cytoplasm
    Protein Attributes:
    Sequence length:
    724
    Sequence:
    50:
    MSFPKAPLKR | FNDPSGCAPS | PGAYDVKTLE | VLKGPVSFQK | SQRFKQQKES | 
    100:
    KQNLNVDKDT | TLPASARKVK | SSESKESQKN | DKDLKILEKE | IRVLLQERGA | 
    150:
    QDRRIQDLET | ELEKMEARLN | AALREKTSLS | ANNATLEKQL | IELTRTNELL | 
    200:
    KSKFSENGNQ | KNLRILSLEL | MKLRNKRETK | MRGMMAKQEG | MEMKLQVTQR | 
    250:
    SLEESQGKIA | QLEGKLVSIE | KEKIDEKSET | EKLLEYIEEI | SCASDQVEKY | 
    300:
    KLDIAQLEEN | LKEKNDEILS | LKQSLEENIV | ILSKQVEDLN | VKCQLLEKEK | 
    350:
    EDHVNRNREH | NENLNAEMQN | LKQKFILEQQ | EREKLQQKEL | QIDSLLQQEK | 
    400:
    ELSSSLHQKL | CSFQEEMVKE | KNLFEEELKQ | TLDELDKLQQ | KEEQAERLVK | 
    450:
    QLEEEAKSRA | EELKLLEEKL | KGKEAELEKS | SAAHTQATLL | LQEKYDSMVQ | 
    500:
    SLEDVTAQFE | SYKALTASEI | EDLKLENSSL | QEKAAKAGKN | AEDVQHQILA | 
    550:
    TESSNQEYVR | MLLDLQTKSA | LKETEIKEIT | VSFLQKITDL | QNQLKQQEED | 
    600:
    FRKQLEDEEG | RKAEKENTTA | ELTEEINKWR | LLYEELYNKT | KPFQLQLDAF | 
    650:
    EVEKQALLNE | HGAAQEQLNK | IRDSYAKLLG | HQNLKQKIKH | VVKLKDENSQ | 
    700:
    LKSEVSKLRC | QLAKKKQSET | KLQEELNKVL | GIKHFDPSKA | FHHESKENFA | 
    724:
    LKTPLKEGNT | NCYRAPMECQ | ESWK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    MIM:
    SMR:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Hyaluronan mediated motility receptor
    Cat.:
    E9486h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Hyaluronan mediated motility receptor
    Cat.:
    E9486r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Hyaluronan mediated motility receptor
    Cat.:
    E9486m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hyaluronan mediated motility receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Human Hyaluronan mediated motility receptor
    Cat.:
    U9486h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Hyaluronan mediated motility receptor
    Cat.:
    U9486m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Hyaluronan mediated motility receptor
    Cat.:
    P9486Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hyaluronan mediated motility receptor
    Polyclonal Antibody for Human Hyaluronan mediated motility receptor
    Cat.:
    P9486Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Hyaluronan mediated motility receptor
    Monoclonal Antibody for Human Hyaluronan mediated motility receptor
    Monoclonal Antibody for Human Hyaluronan mediated motility receptor
    Protein for Human Hyaluronan mediated motility receptor
    Protein for Human Hyaluronan mediated motility receptor
    Protein for Human Hyaluronan mediated motility receptor

    R&D Technical Data

             12% SDS-PAGE Analysis

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.3%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤8.5%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    91-106

    Plasma

    99

    90-107

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    90-99%

    92-101%

    92-102%

    92-106%

    EDTA plasma(n=5)

    92-98%

    94-105%

    90-101%

    95-107%

    heparin plasma(n=5)

    94-104%

     

    94-108%

    101-107%

    93-109%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The characterization of a human RHAMM cDNA: conservation of the hyaluronan-binding domains."
      Wang C. , Entwistle J. , Hou G. , Li Q. , Turley E.A.
      Gene174:299-306(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
      tissue: Mammary gland.
    2. 2.
      "The human hyaluronan receptor RHAMM is expressed as an intracellular protein in breast cancer cells."
      Assmann V. , Marshall J.F. , Fieber C. , Hofmann M. , Hart I.R.
      J. Cell Sci.111:1685-1694(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);ALTERNATIVE SPLICING (ISOFORM 2);CHARACTERIZATION
      tissue: Mammary carcinoma.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 4);VARIANTS ALA-368 AND VAL-484
      tissue: Thymus.
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANTS CYS-92; ALA-368 AND VAL-484
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-20;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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